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KMID : 0670719970020010001
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Journal of the Korean Society Hyperthermia Oncology
1997 Volume.2 No. 1 p.1 ~ p.12
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Role of Radiotherapy in Cancer Treatment
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Noah C Choi
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Abstract
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Radiation therapy has played an important role in the management of cancer ever
since its discovery. With a better understanding of radiation biology, the use of ionizing
radiation has expanded in the management of cancer and clinical results have improved.
The role of radiotherapy in cancer treatment may be presented according to the
metastatic potential of various tumor types.
A. Radiotherapy for malignant tumors with low metastatic potential.
Radiation therapy can achieve effective local tumor control and a high cure rate in
this type of tumor. Since local tumor control equals almost the cure rate, high dose
radiotherapy with good preservation of normal tissue is recommended. Early stage head
and neck cancer carries a cure rate of≥85% with radiotherapy alone. Even though
surgery provides a cure rate equal to that of radiotherapy, organ preservation is better
achieved with radiotherapy. Therefore, radiation therapy is preferred choice of treatment
and surgery is reserved as a salvage procedure. Even in advanced stage tumor,
radiotherapy Plays an integral Part of multi-modality therapy.
B. Radiotherapy lout organ preservation in malignant tumors with high metastatic
potential.
Radiation therapy has become a preferred treatment to surgery even in cancer with
high metastatic potential. With an advancement in tumor localization (MRI, PET),
treatment delivery (CT simulation, 3-D planning, conformal therapy, stereotactic therapy)
and individualized dose-fractionation schedule, radiotherapy has been able to achieve a
preservation of organ/function in early stage cancer of breast, prostate, urinary bladder
and sarcoma of limbs. This is achieved with a combination of chromo-radiotherapy and
minimal surgery.
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KEYWORD
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